Delarge, Jacques E.: шукати на сайті Z-Library

Pascal de Tullio, Apostolos Felikidis, Bernard Pirotte, Jean-François Liégeois, Monique Stachow, Jacques Delarge, Attilio Ceccato, Philippe Hubert, Jacques Crommen, Joseph Géczy

Рік:

1996

Мова:

english

Файл:

PDF, 345 KB

english, 1996

First Preparative Enantiomer Resolution of Pirlindole, a Potent Antidepressant Drug

Журнал:

Helvetica Chimica Acta

Рік:

1998

Мова:

english

Файл:

PDF, 526 KB

english, 1998

Pyridobenzoxazepine and Pyridobenzothiazepine Derivatives as Potential Central Nervous System Agents: Synthesis and Neurochemical Study

Liegeois, Jean Francois F., Rogister, Francoise A., Bruhwyler, Jacques, Damas, Jacques, Nguyen, Thuy Phuong, Inarejos, Maria Olvido, Chleide, Eric M. G., Mercier, Michel G. A., Delarge, Jacques E.

Журнал:

Leval, Xavier, Julemont, Fabien, Delarge, Jacques, Pirotte, Bernard, Dogne, Jean-Michel

Рік:

1994

Мова:

english

Файл:

PDF, 935 KB

english, 1994

New Trends in Dual 5-LOX / COX Inhibition

Журнал:

Pascal De Tullio, Attilio Ceccato, Jean-François Liégeois, Bernard Pirotte, Apostolos Felikidis, Monique Stachow, Philippe Hubert, Jacques Crommen, Joseph Géczy, Jacques Delarge

Рік:

2002

Мова:

english

Файл:

PDF, 122 KB

english, 2002

Effective resolution of racemic pirlindole at the preparative scale

Журнал:

Chirality

Рік:

1999

Мова:

english

Файл:

PDF, 122 KB

english, 1999

ChemInform Abstract: Synthesis and Structural Studies of 3-Alkylamino-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-Dioxides: A New Class of Heterocyclic Compounds with Therapeutical Promises.

Pascal de Tullio, Raogo Ouedraogo, Leon Dupont, Fabian Somers, Stephane Boverie, Jean-Michel Dogne, Jacques Delarge, Bernard Pirotte

Журнал:

ChemInform

Рік:

1999

Мова:

english

Файл:

PDF, 31 KB

english, 1999

ChemInform Abstract: Terbogrel, a Dual-Acting Agent for Thromboxane Receptor Antagonism and Thromboxane Synthase Inhibition.

Catherine Michaux, Bernadette Norberg, Jean-Michel Dogne, Francois Durant, Bernard Masereel, Jacques Delarge, Johan Wouters

Журнал:

ChemInform

Рік:

2001

Файл:

PDF, 29 KB

2001

New Alkoxypyridine-sulfonamides: Synthesis, Biological Evaluation, and Physicochemical Properties

Jean-François Liegéois, Georges Dive, Léon Dupont, Jacques Delarge

Журнал:

Helvetica Chimica Acta

Рік:

1991

Мова:

english

Файл:

PDF, 498 KB

english, 1991

Structural Study of Pinacidil, a Potassium-Channel Opener Belonging to the chemical class of N-alkyl-N″-cyano-N′-pyridylguanidines

Bernard Pirotte, Pascal de Tullio, Bernard Masereel, Marc Schynts, Jacques Delarge, Léon Dupont

Журнал:

Helvetica Chimica Acta

Рік:

1993

Мова:

english

Файл:

PDF, 442 KB

english, 1993

First synthesis of 4-substituted benzenesulfonylcyanoguanidines

Bernard Masereel, Philippe Lebrun, Jean Michel Dogné, Pascal de Tullio, Bernard Pirotte, Lionel Pochet, Ousman Diouf, Jacques Delarge

Журнал:

Tetrahedron Letters

Рік:

1996

Мова:

english

Файл:

PDF, 112 KB

english, 1996

Antipsychotics and neuropeptides: The atypical profile of CI-943 and its relationship to neurotensin

Jean-François Liégeois, Pascal Bonaventure, Jacques Delarge, Jacques Damas

Журнал:

Neuroscience & Biobehavioral Reviews

Рік:

1995

Мова:

english

Файл:

PDF, 1.11 MB

english, 1995

Study of the ring closure reaction of o-aminoarylsulfonamides with 1,1′-thiocarbonyldiimidazole.

Pascal de Tullio, Bernard Pirotte, Fabian Somers, Stéphane Boverie, Fabrice Lacan, Jacques Delarge

Журнал:

Françoise Rogister, Didier Laeckmann, Pierre-Olivier Plasman, Françoise Van Eylen, Marianne Ghyoot, Carine Maggetto, Jean-François Liégeois, Joseph Géczy, André Herchuelz, Jacques Delarge, Bernard Mas

Рік:

1998

Мова:

english

Файл:

PDF, 465 KB

english, 1998

Novel inhibitors of the sodium–calcium exchanger: benzene ring analogues of N-guanidino substituted amiloride derivatives

Журнал:

European Journal of Medicinal Chemistry

Рік:

2001

Мова:

english

Файл:

PDF, 264 KB

english, 2001

Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition

Catherine Michaux, Stéphanie Rolin, Jean-Michel Dogné, François Durant, Bernard Masereel, Jacques Delarge, Johan Wouters

Журнал:

Bioorganic & Medicinal Chemistry Letters

Рік:

2001

Мова:

english

Файл:

PDF, 260 KB

english, 2001

The behavioral effects of acute and chronic JL 13, a putative antipsychotic, inCebusnon-human primates

Daniel E. Casey, Jacques Bruhwyler, Jacques Delarge, Joseph Géczy, Jean-François Liégeois

Журнал:

Psychopharmacology

Рік:

2001

Мова:

english

Файл:

PDF, 126 KB

english, 2001

Synthesis and structural studies of a new class of heterocyclic compounds: 1,2,4-Pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides

Pascal de Tullio, Bernard Pirotte, Léon Dupont, Bernard Masereel, Didier Laeckmann, Tchao Podona, Ousmane Diouf, Philippe Lebrun, Jacques Delarge

Журнал:

Рік:

1995

Мова:

english

Файл:

PDF, 724 KB

english, 1995

“Fries like” rearrangement: A novel and efficient method for the synthesis of 6-acyl-2(3H)-benzoxazolones and 6-acyl-2(3H)-benzothiazolones

Huseyin Ucar, Kim Van derpoorten, Paul Depovere, Daniel Lesieur, Majed Isa, Bernard Masereel, Jacques Delarge, Jacques H. Poupaert

Журнал:

Рік:

1998

Мова:

english

Файл:

PDF, 426 KB

english, 1998

Synthesis and structural studies of 3-Alkylamino-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides: a new class of heterocyclic compounds with therapeutical promises

Pascal de Tullio, Raogo Ouedraogo, Léon Dupont, Fabian Somers, Stéphane Boverie, Jean-Michel Dogné, Jacques Delarge, Bernard Pirotte

Журнал:

Johan Wouters, Catherine Michaux, François Durant, Jean Michel Dogné, Jacques Delarge, Bernard Masereel

Рік:

1999

Мова:

english

Файл:

PDF, 713 KB

english, 1999

Isosterism among analogues of torasemide: conformational, electronic and lipophilicity properties

Журнал:

European Journal of Medicinal Chemistry

Рік:

2000

Мова:

english

Файл:

PDF, 175 KB

english, 2000

Synthesis and biological evaluation of aroylguanidines related to amiloride as inhibitors of the human platelet Na+/H+ exchanger

Didier Laeckmann, Françoise Rogister, Jean-Victor Dejardin, Christelle Prosperi-Meys, Joseph Géczy, Jacques Delarge, Bernard Masereel

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2002

Мова:

english

Файл:

PDF, 262 KB

english, 2002

Preparation and pharmacological evaluation of the R- and S-enantiomers of 3-(2′-butylamino)-4H- and 3-(3′-methyl-2′-butylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxide, two tissue selective ATP-sensitive potassium channel openers

Smail Khelili, Pascal de Tullio, Philippe Lebrun, Marianne Fillet, Marie-Hélène Antoine, Raogo Ouedraogo, Léon Dupont, Jeanine Fontaine, Apostolos Felekidis, Gérard Leclerc, Jacques Delarge, Bernard P

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

1999

Мова:

english

Файл:

PDF, 205 KB

english, 1999

Pharmacology of the Thromboxane Receptor Antagonist and Thromboxane Synthase Inhibitor BM-531

Jean-Michel Dogné, Stéphanie Rolin, Xavier de Leval, Patricia Benoit, Philippe Neven, Jacques Delarge, Philippe Kolh, Jacques Damas, Jean-Louis David, Bernard Masereel

Журнал:

Cardiovascular Therapeutics

Рік:

2001

Мова:

english

Файл:

PDF, 100 KB

english, 2001

4H-1,2,4-Pyridothiadiazine 1,1-Dioxides and 2,3-Dihydro-4H-1,2,4-pyridothiadiazine 1,1-Dioxides Chemically Related to Diazoxide and Cyclothiazide as Powerful Positive Allosteric Modulators of (R/S)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors: Design, Synthesis, Pharmacology, and Structure−Activity Relationships

Pirotte, Bernard, Podona, Tchao, Diouf, Ousmane, de Tullio, Pascal, Lebrun, Philippe, Dupont, Léon, Somers, Fabian, Delarge, Jacques, Morain, Philippe, Lestage, Pierre

Журнал:

Jean-François Liégeois, Vincent Seutin, Jacqueline Scuvée-Moreau, Albert Dresse, Jacques Bruhwyler, Joseph Géczy, Jacques Delarge, Jacques Damas

Рік:

1998

Мова:

english

Файл:

PDF, 436 KB

english, 1998

Effects of JL 3, a putative antidepressant, on rat noradrenergic and serotonergic systems

Журнал:

European Journal of Pharmaceutical Sciences

Рік:

1999

Мова:

english

Файл:

PDF, 264 KB

english, 1999

Pyridothiadiazinedioxides structurally related to quinazolinones cholecystokinin/gastrin receptor ligands: synthesis and biological evaluation

Bernard Pirotte, Pascal de Tullio, Tchao Podona, Ousmane Diouf, Daniel Dewalque, Philippe Neven, Bernard Masereel, Daniel-Henri Caignard P, Pierre Renard, Jacques Delarge

Журнал:

Рік:

1998

Мова:

english

Файл:

PDF, 238 KB

english, 1998

Oxidation Sensitivity May Be a Useful Tool for the Detection of the Hematotoxic Potential of Newly Developed Molecules: Application to Antipsychotic Drugs

Jean-François Liégeois, Jacques Bruhwyler, Christine Petit, Jacques Damas, Jacques Delarge, Joseph Géczy, Jean-Michel Kauffmann, Maurice Lamy, Herbert Meltzer, Ange Mouithys-Mickalad

Журнал:

Archives of Biochemistry and Biophysics

Рік:

1999

Мова:

english

Файл:

PDF, 133 KB

english, 1999

JL 13, a Potential Successor to Clozapine, Is Less Sensitive to Oxidative Phenomena

Jean-François Liégeois, Ange Mouithys-Mickalad, Jacques Bruhwyler, Jacques Delarge, Christine Petit, Jean-Michel Kauffmann, Maurice Lamy

Журнал:

Biochemical and Biophysical Research Communications

Рік:

1997

Мова:

english

Файл:

PDF, 116 KB

english, 1997

Na+,2Cl−,K+ cotransport system as a marker of antihypertensive activity of new torasemide derivatives

Bernard Masereel, Patrizia Ferrari, Marra Ferrandi, Bernard Pirotte, Marc Schynts, Paolo Parenti, Jacques Delarge

Журнал:

Jean-François Liégeois, Jacques Bruhwyler, Jacques Damas, Françoise Rogister, Bernard Masereel, Joseph Geczy, Jacques Delarge

Рік:

1992

Мова:

english

Файл:

PDF, 753 KB

english, 1992

Modulation of the clozapine structure increases its selectivity for the dopamine D4 receptor

Журнал:

Jean-François Liégeois, Jacques Bruhwyler, Jean-Claude Hendrick, Jacques Delarge, Jean-Jacques Legros, Jacques Damas

Рік:

1995

Мова:

english

Файл:

PDF, 225 KB

english, 1995

Minimal effects of JL 13, a pyridobenzoxazepine derivative with an antipsychotic potential, on circulating prolactin levels in male rats

Журнал:

Neuroscience Letters

Рік:

2002

Мова:

english

Файл:

PDF, 76 KB

english, 2002

Synthesis and Biological Evaluation of New 3-Aralkylamino-2-aryl-2H-1,2,4-pyridothiadiazine 1,1-dioxides as Potential CCK-Receptor Ligands

PASCAL DE TULLIO, BERNARD PIROTTE, PHILIPPE NEVEN, BERNARD MASEREEL, DANIEL DEWALQUE, OUSMANE DIOUF, TCHAO PODONA, DANIEL CAIGNARD, PIERRE RENARD, JACQUES DELARGE

Журнал:

Journal of Pharmacy and Pharmacology

Рік:

1997

Мова:

english

Файл:

PDF, 954 KB

english, 1997

3-(Alkylamino)-4H-pyrido[4,3-e]1,2,4-thiadiazine 1,1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: a new class of potassium channel openers?

Pirotte, Bernard, de Tullio, Pascal, Lebrun, Philippe, Antoine, Marie Helene, Fontaine, Jeanine, Masereel, Bernard, Schynts, Marc, Dupont, Leon, Herchuelz, Andre, Delarge, Jacques

Журнал:

Liegeois, Jean Francois F., Bruhwyler, Jacques, Damas, Jacques, Nguyen, Thuy Phuong, Chleide, Eric M. G., Mercier, Michel G. A., Rogister, Francoise A., Delarge, Jacques E.

Рік:

1993

Мова:

english

Файл:

PDF, 391 KB

english, 1993

New pyridobenzodiazepine derivatives as potential antipsychotics: synthesis and neurochemical study

Журнал:

Рік:

1993

Мова:

english

Файл:

PDF, 1.07 MB

english, 1993

Esters and Amides of 6-(Chloromethyl)-2-oxo-2 H -1-benzopyran-3-carboxylic Acid as Inhibitors of α-Chymotrypsin: Significance of the “Aromatic” Nature of the Novel Ester-Type Coumarin for Strong Inhibitory Activity

Pochet, Lionel, Doucet, Caroline, Schynts, Marc, Thierry, Nicole, Boggetto, Nicole, Pirotte, Bernard, Jiang, Kai Y., Masereel, Bernard, de Tullio, Pascal, Delarge, Jacques, Reboud-Ravaux, Michèle

Журнал:

Mouithys-Mickalad, Ange, Kauffmann, Jean-Michel, Petit, Christine, Bruhwyler, Jacques, Liao, Yi, Wikström, Håkan, Damas, Jacques, Delarge, Jacques, Deby-Dupont, Ginette, Géczy, Joseph, Liégeois, Jean-

Рік:

1996

Мова:

english

Файл:

PDF, 193 KB

english, 1996

Electrooxidation Potential as a Tool in the Early Screening for New Safer Clozapine-like Analogues

Журнал:

Ucar, Huseyin, Van derpoorten, Kim, Cacciaguerra, Silvia, Spampinato, Santi, Stables, James P., Depovere, Paul, Isa, Majed, Masereel, Bernard, Delarge, Jacques, Poupaert, Jacques H.

Рік:

2001

Мова:

english

Файл:

PDF, 89 KB

english, 2001

Synthesis and Anticonvulsant Activity of 2(3 H )-Benzoxazolone and 2(3 H )-Benzothiazolone Derivatives

Журнал:

Рік:

1998

Мова:

english

Файл:

PDF, 112 KB

english, 1998

Original 2-Alkylamino-6-halogenoquinazolin-4(3 H )-ones and K ATP Channel Activity

Somers, Fabian, Ouedraogo, Raogo, Antoine, Marie-Hélène, de Tullio, Pascal, Becker, Bénédicte, Fontaine, Jeanine, Damas, Jacques, Dupont, Léon, Rigo, Benoit, Delarge, Jacques, Lebrun, Philippe, Pirott

Журнал:

Doucet, Caroline, Pochet, Lionel, Thierry, Nicole, Pirotte, Bernard, Delarge, Jacques, Reboud-Ravaux, Michèle

Рік:

2001

Мова:

english

Файл:

PDF, 134 KB

english, 2001

6-Substituted 2-Oxo-2 H -1-benzopyran-3-carboxylic Acid as a Core Structure for Specific Inhibitors of Human Leukocyte Elastase †

Журнал:

Liégeois, Jean-François, Eyrolles, Laurence, Ellenbroek, Bart A., Lejeune, Christel, Carato, Pascal, Bruhwyler, Jacques, Géczy, Joseph, Damas, Jacques, Delarge, Jacques

Рік:

1999

Мова:

english

Файл:

PDF, 228 KB

english, 1999

New Pyridobenzodiazepine Derivatives: Modifications of the Basic Side Chain Differentially Modulate Binding to Dopamine (D 4.2 , D 2L ) and Serotonin (5-HT 2A ) Receptors

Журнал:

Delarge, Jacques, Dogné, Jean-Michel, Julémont, Fabien, Leval, Xavier de, Pirotte, Bernard, Sanna, Vanna

Рік:

2002

Мова:

english

Файл:

PDF, 236 KB

english, 2002

Advances in the field of COX-2 inhibition

Журнал:

Expert Opinion on Therapeutic Patents

Рік:

2002

Мова:

english

Файл:

PDF, 276 KB

english, 2002

Synthesis and Anticonvulsant Activity of 2(3 H )-Benzoxazolone and 2(3 H )-Benzothiazolone Derivatives

Ucar, Huseyin, Van derpoorten, Kim, Cacciaguerra, Silvia, Spampinato, Santi, Stables, James P., Depovere, Paul, Isa, Majed, Masereel, Bernard, Delarge, Jacques, Poupaert, Jacques H.

Журнал:

Pirotte, Bernard, Tullio, Pascal De, Masereel, Bernard, Schynts, Marc, Delarge, Jacques, Dupont, Léon, Thunus, Léopold

Рік:

1998

Мова:

english

Файл:

PDF, 12 KB

english, 1998

4-Acylamino-4 H -1,2,4-triazoles and related structures: new investigations of their chemical and physicochemical properties associated with their particular exocyclic amide function

Журнал:

Canadian Journal of Chemistry

Рік:

1993

Мова:

english

Файл:

PDF, 650 KB

english, 1993

Recent developments of thromboxane modulators

Masereel, Bernard, Dogné, Jean-Michel, Delarge, Jacques, Leval, Xavier de

Журнал:

Expert Opinion on Therapeutic Patents

Рік:

2001

Мова:

english

Файл:

PDF, 186 KB

english, 2001

New Trends in Thromboxane and Prostacyclin Modulators

Dogne, Jean, Leval, Xavier, Delarge, Jacques, David, Jean, Masereel, Bernard

Журнал:

Рік:

2000

Файл:

PDF, 117 KB

2000

New Trends in Thromboxane and Prostacyclin Modulators

Dogne, Jean, Leval, Xavier, Delarge, Jacques, David, Jean, Masereel, Bernard

Журнал:

Dogne, Jean-Michel, Leval, Xavier, Benoit, Patricia, Delarge, Jacques, Masereel, Bernard, David, Jean-Louis

Рік:

2000

Мова:

english

Файл:

PDF, 117 KB

english, 2000

Recent Advances in Antiplatelet Agents

Журнал: